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Novel roles for HMGA2 isoforms in regulating oxidative stress and sensitizing to RSL3-Induced ferroptosis in prostate cancer cells

Oxidative stress is increased in several cancers including prostate cancer, and is currently being exploited in cancer therapy to induce ferroptosis, a novel nonapoptotic form of cell death. High mobility group A2 (HMGA2), a non-histone protein up-regulated in several cancers, can be truncated due t...

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Detalles Bibliográficos
Autores principales: Campbell, Taaliah, Hawsawi, Ohuod, Henderson, Veronica, Dike, Precious, Hwang, Bor-Jang, Liadi, Yusuf, White, ElShaddai Z., Zou, Jin, Wang, GuangDi, Zhang, Qiang, Bowen, Nathan, Scott, Derrick, Hinton, Cimona V., Odero-Marah, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126861/
https://www.ncbi.nlm.nih.gov/pubmed/37113783
http://dx.doi.org/10.1016/j.heliyon.2023.e14810