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498 Structural Determination of the CqsR CACHE Domain and its Autoinducer

OBJECTIVES/GOALS: Our goal is to determine the structure of the CACHE domain of the Vibrio cholerae quorum sensing receptor CqsR as well as its autoinducer (AI). We are performing X-ray crystallography on the protein in its apo form, with the fractions containing the AI, and with known ligand ethano...

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Detalles Bibliográficos
Autores principales: Guarnaccia, Andrew, Ng, Wei-Lung, Steenhaut, Anjali, Olenic, Sandra, Perez, Lark, Neiditch, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10126886/
http://dx.doi.org/10.1017/cts.2023.503