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Efficient manipulation of gene expression using Natronobacterium gregoryi Argonaute in zebrafish
BACKGROUND: Natronobacterium gregoryi Argonaute (NgAgo) was found to reduce mRNA without generating detectable DNA double-strand breaks in a couple of endogenous genes in zebrafish, suggesting its potential as a tool for gene knockdown. However, little is known about how it interacts with nucleic ac...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127001/ https://www.ncbi.nlm.nih.gov/pubmed/37095525 http://dx.doi.org/10.1186/s12915-023-01599-x |