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Efficient manipulation of gene expression using Natronobacterium gregoryi Argonaute in zebrafish

BACKGROUND: Natronobacterium gregoryi Argonaute (NgAgo) was found to reduce mRNA without generating detectable DNA double-strand breaks in a couple of endogenous genes in zebrafish, suggesting its potential as a tool for gene knockdown. However, little is known about how it interacts with nucleic ac...

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Detalles Bibliográficos
Autores principales:	Dong, Zhangji, Chen, Xu, Zhuo, Run, Li, Yuanyuan, Zhou, Zhihao, Sun, Ying, Liu, Yan, Liu, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127001/ https://www.ncbi.nlm.nih.gov/pubmed/37095525 http://dx.doi.org/10.1186/s12915-023-01599-x

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