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Single-cell transcriptome analysis of NEUROG3+ cells during pancreatic endocrine differentiation with small molecules

The efficiency of inducing human embryonic stem cells into NEUROG3+ pancreatic endocrine cells is a bottleneck in stem cell therapy for diabetes. To understand the cell properties and fate decisions during differentiation, we analyzed the modified induction method using single-cell transcriptome and...

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Detalles Bibliográficos
Autores principales: Li, Jin, Chen, Junru, Luo, Xiaoyu, Lu, Guangxiu, Lin, Ge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127065/
https://www.ncbi.nlm.nih.gov/pubmed/37098639
http://dx.doi.org/10.1186/s13287-023-03338-z