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Single-cell transcriptome analysis of NEUROG3+ cells during pancreatic endocrine differentiation with small molecules
The efficiency of inducing human embryonic stem cells into NEUROG3+ pancreatic endocrine cells is a bottleneck in stem cell therapy for diabetes. To understand the cell properties and fate decisions during differentiation, we analyzed the modified induction method using single-cell transcriptome and...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127065/ https://www.ncbi.nlm.nih.gov/pubmed/37098639 http://dx.doi.org/10.1186/s13287-023-03338-z |