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Beginner's Guide on the Use of PAML to Detect Positive Selection
The CODEML program in the PAML package has been widely used to analyze protein-coding gene sequences to estimate the synonymous and nonsynonymous rates (d(S) and d(N)) and to detect positive Darwinian selection driving protein evolution. For users not familiar with molecular evolutionary analysis, t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127084/ https://www.ncbi.nlm.nih.gov/pubmed/37096789 http://dx.doi.org/10.1093/molbev/msad041 |