Beginner's Guide on the Use of PAML to Detect Positive Selection

The CODEML program in the PAML package has been widely used to analyze protein-coding gene sequences to estimate the synonymous and nonsynonymous rates (d(S) and d(N)) and to detect positive Darwinian selection driving protein evolution. For users not familiar with molecular evolutionary analysis, t...

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Detalles Bibliográficos
Autores principales: Álvarez-Carretero, Sandra, Kapli, Paschalia, Yang, Ziheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Protocols
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127084/
https://www.ncbi.nlm.nih.gov/pubmed/37096789
http://dx.doi.org/10.1093/molbev/msad041

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