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Submersion and hypoxia inhibit alveolar epithelial Na(+) transport through ERK/NF-κB signaling pathway

BACKGROUND: Hypoxia is associated with many respiratory diseases, partly due to the accumulation of edema fluid and mucus on the surface of alveolar epithelial cell (AEC), which forms oxygen delivery barriers and is responsible for the disruption of ion transport. Epithelial sodium channel (ENaC) on...

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Detalles Bibliográficos
Autores principales: Zhou, Wei, Hou, Yapeng, Yu, Tong, Wang, Tingyu, Ding, Yan, Nie, Hongguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127099/
https://www.ncbi.nlm.nih.gov/pubmed/37095538
http://dx.doi.org/10.1186/s12931-023-02428-z