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Alpha-SNAP (M105I) mutation promotes neuronal differentiation of neural stem/progenitor cells through overactivation of AMPK

Background: The M105I point mutation in α-SNAP (Soluble N-ethylmaleimide-sensitive factor attachment protein-alpha) leads in mice to a complex phenotype known as hyh (hydrocephalus with hop gait), characterized by cortical malformation and hydrocephalus, among other neuropathological features. Studi...

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Detalles Bibliográficos
Autores principales: Bustamante-Barrientos, Felipe A., Méndez-Ruette, Maxs, Molina, Luis, Koning, Tania, Ehrenfeld, Pamela, González, Carlos B., Wyneken, Ursula, Henzi, Roberto, Bátiz, Luis Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127105/
https://www.ncbi.nlm.nih.gov/pubmed/37113766
http://dx.doi.org/10.3389/fcell.2023.1061777