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Alpha-SNAP (M105I) mutation promotes neuronal differentiation of neural stem/progenitor cells through overactivation of AMPK
Background: The M105I point mutation in α-SNAP (Soluble N-ethylmaleimide-sensitive factor attachment protein-alpha) leads in mice to a complex phenotype known as hyh (hydrocephalus with hop gait), characterized by cortical malformation and hydrocephalus, among other neuropathological features. Studi...
Autores principales: | Bustamante-Barrientos, Felipe A., Méndez-Ruette, Maxs, Molina, Luis, Koning, Tania, Ehrenfeld, Pamela, González, Carlos B., Wyneken, Ursula, Henzi, Roberto, Bátiz, Luis Federico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127105/ https://www.ncbi.nlm.nih.gov/pubmed/37113766 http://dx.doi.org/10.3389/fcell.2023.1061777 |
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