H(2)O(2) transit through the mitochondrial intermembrane space promotes tumor cell growth in vitro and in vivo

Cancer cells experience increased levels of oxidant stress as a consequence of oncogene activation, nucleotide biosynthesis, and growth factor receptor signaling. Mitochondria contribute to this redox stress by generating reactive oxygen species (ROS) along the electron transport chain, which are re...

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Detalles Bibliográficos
Autores principales: Sabharwal, Simran S., Dudley, V. Joseph, Landwerlin, Charlène, Schumacker, Paul T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127139/
https://www.ncbi.nlm.nih.gov/pubmed/36935009
http://dx.doi.org/10.1016/j.jbc.2023.104624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127139/
https://www.ncbi.nlm.nih.gov/pubmed/36935009
http://dx.doi.org/10.1016/j.jbc.2023.104624

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