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H(2)O(2) transit through the mitochondrial intermembrane space promotes tumor cell growth in vitro and in vivo
Cancer cells experience increased levels of oxidant stress as a consequence of oncogene activation, nucleotide biosynthesis, and growth factor receptor signaling. Mitochondria contribute to this redox stress by generating reactive oxygen species (ROS) along the electron transport chain, which are re...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127139/ https://www.ncbi.nlm.nih.gov/pubmed/36935009 http://dx.doi.org/10.1016/j.jbc.2023.104624 |