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Mitogen-Activated Protein Kinase Phosphatases: No Longer Undruggable?

Phosphatases and kinases maintain an equilibrium of dephosphorylated and phosphorylated proteins, respectively, that are required for critical cellular functions. Imbalance in this equilibrium or irregularity in their function causes unfavorable cellular effects that have been implicated in the deve...

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Detalles Bibliográficos
Autores principales: Shillingford, Shanelle R., Bennett, Anton M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127142/
https://www.ncbi.nlm.nih.gov/pubmed/36662585
http://dx.doi.org/10.1146/annurev-pharmtox-051921-121923