Deep Annotation of Donated Chemical Probes (DCP) in Organotypic Human Liver Cultures and Patient-Derived Organoids from Tumor and Normal Colorectum

[Image: see text] Well-characterized small molecules are essential tools for studying the biology and therapeutic relevance of a target protein. However, many compounds reported in the literature and routinely studied in biomedical research lack the potency and selectivity required for mechanistic c...

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Detalles Bibliográficos
Autores principales: Tredup, Claudia, Ndreshkjana, Benardina, Schneider, Natalie S., Tjaden, Amelie, Kemas, Aurino M., Youhanna, Sonia, Lauschke, Volker M., Berger, Benedict-Tilman, Krämer, Andreas, Berger, Lena M., Röhm, Sandra, Knapp, Stefan, Farin, Henner F., Müller, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127199/
https://www.ncbi.nlm.nih.gov/pubmed/36944371
http://dx.doi.org/10.1021/acschembio.2c00877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127199/
https://www.ncbi.nlm.nih.gov/pubmed/36944371
http://dx.doi.org/10.1021/acschembio.2c00877

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