Targeted Protein Degradation through E2 Recruitment

[Image: see text] Targeted protein degradation (TPD) with proteolysis targeting chimeras (PROTACs), heterobifunctional compounds consisting of protein targeting ligands linked to recruiters of E3 ubiquitin ligases, has arisen as a powerful therapeutic modality to induce the proximity of target prote...

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Detalles Bibliográficos
Autores principales: Forte, Nafsika, Dovala, Dustin, Hesse, Matthew J., McKenna, Jeffrey M., Tallarico, John A., Schirle, Markus, Nomura, Daniel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127205/
https://www.ncbi.nlm.nih.gov/pubmed/36940189
http://dx.doi.org/10.1021/acschembio.3c00040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127205/
https://www.ncbi.nlm.nih.gov/pubmed/36940189
http://dx.doi.org/10.1021/acschembio.3c00040

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