Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues

The availability of an expanded genetic code opens exciting new opportunities in enzyme design and engineering. In this regard histidine analogues have proven particularly versatile, serving as ligands to augment metalloenzyme function and as catalytic nucleophiles in designed enzymes. The ability t...

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Detalles Bibliográficos
Autores principales: Taylor, Christopher J., Hardy, Florence J., Burke, Ashleigh J., Bednar, Riley M., Mehl, Ryan A., Green, Anthony P., Lovelock, Sarah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127257/
https://www.ncbi.nlm.nih.gov/pubmed/37051694
http://dx.doi.org/10.1002/pro.4640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127257/
https://www.ncbi.nlm.nih.gov/pubmed/37051694
http://dx.doi.org/10.1002/pro.4640

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