Cargando…
Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues
The availability of an expanded genetic code opens exciting new opportunities in enzyme design and engineering. In this regard histidine analogues have proven particularly versatile, serving as ligands to augment metalloenzyme function and as catalytic nucleophiles in designed enzymes. The ability t...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127257/ https://www.ncbi.nlm.nih.gov/pubmed/37051694 http://dx.doi.org/10.1002/pro.4640 |