Directed Evolution of Aerotolerance in Sulfide-Dependent Thiazole Synthases

[Image: see text] Sulfide-dependent THI4 thiazole synthases could potentially be used to replace plant cysteine-dependent suicide THI4s, whose high protein turnover rates make thiamin synthesis exceptionally energy-expensive. However, sulfide-dependent THI4s are anaerobic or microoxic enzymes and he...

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Detalles Bibliográficos
Autores principales: Gelder, Kristen Van, Oliveira-Filho, Edmar R., García-García, Jorge Donato, Hu, You, Bruner, Steven D., Hanson, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127261/
https://www.ncbi.nlm.nih.gov/pubmed/36920242
http://dx.doi.org/10.1021/acssynbio.2c00512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127261/
https://www.ncbi.nlm.nih.gov/pubmed/36920242
http://dx.doi.org/10.1021/acssynbio.2c00512

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