Synthesis of Benzothiophene-3-carboxylic Esters by Palladium Iodide-Catalyzed Oxidative Cyclization–Deprotection–Alkoxycarbonylation Sequence under Aerobic Conditions

[Image: see text] A palladium-catalyzed carbonylative approach to benzothiophene-3-carboxylic esters, starting from simple and readily available building blocks [2-(methylthio)phenylacetylenes, CO, an alcohol, and O(2) (from air)], is reported. The process is catalyzed by the simple PdI(2)/KI cataly...

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Detalles Bibliográficos
Autores principales: Mancuso, Raffaella, Cuglietta, Simona, Strangis, Romina, Gabriele, Bartolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127270/
https://www.ncbi.nlm.nih.gov/pubmed/35537181
http://dx.doi.org/10.1021/acs.joc.2c00686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127270/
https://www.ncbi.nlm.nih.gov/pubmed/35537181
http://dx.doi.org/10.1021/acs.joc.2c00686

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