Receptor Elimination by E3 Ubiquitin Ligase Recruitment (REULR): A Targeted Protein Degradation Toolbox

[Image: see text] In recent years, targeted protein degradation (TPD) of plasma membrane proteins by hijacking the ubiquitin proteasome system (UPS) or the lysosomal pathway has emerged as a novel therapeutic avenue in drug development to address and inhibit canonically difficult targets. While TPD...

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Detalles Bibliográficos
Autores principales: Siepe, Dirk H., Picton, Lora K., Garcia, K. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127277/
https://www.ncbi.nlm.nih.gov/pubmed/37011906
http://dx.doi.org/10.1021/acssynbio.2c00587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127277/
https://www.ncbi.nlm.nih.gov/pubmed/37011906
http://dx.doi.org/10.1021/acssynbio.2c00587

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