4-Octyl itaconate attenuates LPS-induced acute kidney injury by activating Nrf2 and inhibiting STAT3 signaling

BACKGROUND: Septic acute kidney injury (S-AKI) is the leading form of acute kidney failure among hospitalized patients, and the inflammatory response is involved in this process. 4-octyl itaconate (4-OI) is a multi-target itaconate derivative with potent anti-inflammatory action. However, it remains...

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Detalles Bibliográficos
Autores principales: Xu, Lujun, Cai, Juan, Li, Chenrui, Yang, Ming, Duan, Tongyue, Zhao, Qing, Xi, Yiyun, Sun, Liya, He, Liyu, Tang, Chengyuan, Sun, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127401/
https://www.ncbi.nlm.nih.gov/pubmed/37095432
http://dx.doi.org/10.1186/s10020-023-00631-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127401/
https://www.ncbi.nlm.nih.gov/pubmed/37095432
http://dx.doi.org/10.1186/s10020-023-00631-8

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