Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin

Clostridioides difficile is a Gram-positive opportunistic human pathogen that causes 15,000 deaths annually in the United States, prompting a need for vaccine development. In addition to the important toxins TcdA and TcdB, binary toxin (CDT) plays a significant role in the pathogenesis of certain C....

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Detalles Bibliográficos
Autores principales: Goldsmith, Jory A., Dewar, Vincent, Hermand, Philippe, Blais, Normand, McLellan, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127577/
https://www.ncbi.nlm.nih.gov/pubmed/36951574
http://dx.doi.org/10.1128/jb.00456-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127577/
https://www.ncbi.nlm.nih.gov/pubmed/36951574
http://dx.doi.org/10.1128/jb.00456-22

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