Cargando…
SERINC5 Mediates a Postintegration Block to HIV-1 Gene Expression in Macrophages
HIV-1 antagonizes SERINC5 by redundant mechanisms, primarily through Nef and additionally via envelope glycoprotein. Paradoxically, HIV-1 preserves Nef function to ensure the exclusion of SERINC5 from virion incorporation regardless of the availability of envelope that can confer resistance, suggest...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127607/ https://www.ncbi.nlm.nih.gov/pubmed/36976020 http://dx.doi.org/10.1128/mbio.00166-23 |