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Antifungal Tolerance and Resistance Emerge at Distinct Drug Concentrations and Rely upon Different Aneuploid Chromosomes

Antifungal drug tolerance is a response distinct from resistance, in which cells grow slowly above the MIC. Here, we found that the majority (69.2%) of 133 Candida albicans clinical isolates, including standard lab strain SC5314, exhibited temperature-enhanced tolerance at 37°C and 39°C, and were no...

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Detalles Bibliográficos
Autores principales: Yang, Feng, Scopel, Eduardo F. C., Li, Hao, Sun, Liu-liu, Kawar, Nora, Cao, Yong-bing, Jiang, Yuan-Ying, Berman, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127634/
https://www.ncbi.nlm.nih.gov/pubmed/36877011
http://dx.doi.org/10.1128/mbio.00227-23