Intragranuloma Accumulation and Inflammatory Differentiation of Neutrophils Underlie Mycobacterial ESX-1-Dependent Immunopathology

The conserved ESX-1 type VII secretion system is a major virulence determinant of pathogenic mycobacteria, including Mycobacterium tuberculosis and Mycobacterium marinum. ESX-1 is known to interact with infected macrophages, but its potential roles in regulating other host cells and immunopathology...

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Detalles Bibliográficos
Autores principales: Lienard, Julia, Munke, Kristina, Wulff, Line, Da Silva, Clément, Vandamme, Julien, Laschanzky, Katie, Joeris, Thorsten, Agace, William, Carlsson, Fredric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127687/
https://www.ncbi.nlm.nih.gov/pubmed/37017530
http://dx.doi.org/10.1128/mbio.02764-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127687/
https://www.ncbi.nlm.nih.gov/pubmed/37017530
http://dx.doi.org/10.1128/mbio.02764-22

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