Quorum-Sensing Signaling Molecule 2-Aminoacetophenone Mediates the Persistence of Pseudomonas aeruginosa in Macrophages by Interference with Autophagy through Epigenetic Regulation of Lipid Biosynthesis

Macrophages are crucial components of the host’s defense against pathogens. Recent studies indicate that macrophage functions are influenced by lipid metabolism. However, knowledge of how bacterial pathogens exploit macrophage lipid metabolism for their benefit remains rudimentary. We have shown tha...

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Detalles Bibliográficos
Autores principales: Chakraborty, Arijit, Kabashi, Asel, Wilk, Samuel, Rahme, Laurence G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127747/
https://www.ncbi.nlm.nih.gov/pubmed/37010415
http://dx.doi.org/10.1128/mbio.00159-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10127747/
https://www.ncbi.nlm.nih.gov/pubmed/37010415
http://dx.doi.org/10.1128/mbio.00159-23

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