Dual-Uptake Mode of the Antibiotic Phazolicin Prevents Resistance Acquisition by Gram-Negative Bacteria

Phazolicin (PHZ) is a peptide antibiotic exhibiting narrow-spectrum activity against rhizobia closely related to its producer, Rhizobium sp. strain Pop5. Here, we show that the frequency of spontaneous PHZ-resistant mutants in Sinorhizobium meliloti is below the detection limit. We find that PHZ can...

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Detalles Bibliográficos
Autores principales: Travin, Dmitrii Y., Jouan, Romain, Vigouroux, Armelle, Inaba-Inoue, Satomi, Lachat, Joy, Haq, Fazal, Timchenko, Tatiana, Sutormin, Dmitry, Dubiley, Svetlana, Beis, Konstantinos, Moréra, Solange, Severinov, Konstantin, Mergaert, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128002/
https://www.ncbi.nlm.nih.gov/pubmed/36802165
http://dx.doi.org/10.1128/mbio.00217-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128002/
https://www.ncbi.nlm.nih.gov/pubmed/36802165
http://dx.doi.org/10.1128/mbio.00217-23

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