Cargando…
Genome-Scale CRISPR Screening Reveals Host Factors Required for Ribosome Formation and Viral Replication
Viruses are known to co-opt host machinery for translation initiation, but less is known about which host factors are required for the formation of ribosomes used to synthesize viral proteins. Using a loss-of-function CRISPR screen, we show that synthesis of a flavivirus-encoded fluorescent reporter...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128003/ https://www.ncbi.nlm.nih.gov/pubmed/36809113 http://dx.doi.org/10.1128/mbio.00127-23 |