Genome-Wide CRISPR-Cas9 Screen Identifies SMCHD1 as a Restriction Factor for Herpesviruses

Intrinsic immunity is the frontline of host defense against invading pathogens. To combat viral infection, mammalian hosts deploy cell-intrinsic effectors to block viral replication prior to the onset of innate and adaptive immunity. In this study, SMCHD1 is identified as a pivotal cellular factor t...

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Detalles Bibliográficos
Autores principales: Tian, Xuezhang, Zhou, Yaru, Wang, Shaowei, Gao, Ming, Xia, Yanlin, Li, Yangyang, Zhong, Yunhong, Xu, Wenhao, Bai, Lei, Fu, Bishi, Zhou, Yu, Lee, Hye-Ra, Deng, Hongyu, Lan, Ke, Feng, Pinghui, Zhang, Junjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128004/
https://www.ncbi.nlm.nih.gov/pubmed/37010434
http://dx.doi.org/10.1128/mbio.00549-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128004/
https://www.ncbi.nlm.nih.gov/pubmed/37010434
http://dx.doi.org/10.1128/mbio.00549-23

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