HexSDF Is Required for Synthesis of a Novel Glycolipid That Mediates Daptomycin and Bacitracin Resistance in C. difficile

Clostridioides difficile is a Gram-positive opportunistic pathogen responsible for 250,000 hospital-associated infections, 12,000 hospital-associated deaths, and $1 billion in medical costs in the United States each year. There has been recent interest in using a daptomycin analog, surotomycin, to t...

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Detalles Bibliográficos
Autores principales: Pannullo, Anthony G., Guan, Ziqiang, Goldfine, Howard, Ellermeier, Craig D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128005/
https://www.ncbi.nlm.nih.gov/pubmed/36786594
http://dx.doi.org/10.1128/mbio.03397-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128005/
https://www.ncbi.nlm.nih.gov/pubmed/36786594
http://dx.doi.org/10.1128/mbio.03397-22

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