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Illuminating Siderophore Transporter Functionality with Thiopeptide Antibiotics
The Gram-negative opportunistic pathogen Pseudomonas aeruginosa is a leading cause of infections and mortality in immunocompromised patients. This organism can overcome iron deprivation during infection via the synthesis of two iron-chelating siderophores, pyoverdine and pyochelin, which scavenge ir...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American Society for Microbiology
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128021/ https://www.ncbi.nlm.nih.gov/pubmed/36946760 http://dx.doi.org/10.1128/mbio.03326-22 |