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Adaptation to Overflow Metabolism by Mutations That Impair tRNA Modification in Experimentally Evolved Bacteria

When microbes grow in foreign nutritional environments, selection may enrich mutations in unexpected pathways connecting growth and homeostasis. An evolution experiment designed to identify beneficial mutations in Burkholderia cenocepacia captured six independent nonsynonymous substitutions in the e...

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Detalles Bibliográficos
Autores principales: Muraski, Marc J., Nilsson, Emil M., Fritz, Melissa J., Richardson, Anthony R., Alexander, Rebecca W., Cooper, Vaughn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128029/
https://www.ncbi.nlm.nih.gov/pubmed/36853041
http://dx.doi.org/10.1128/mbio.00287-23