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Adaptation to Overflow Metabolism by Mutations That Impair tRNA Modification in Experimentally Evolved Bacteria
When microbes grow in foreign nutritional environments, selection may enrich mutations in unexpected pathways connecting growth and homeostasis. An evolution experiment designed to identify beneficial mutations in Burkholderia cenocepacia captured six independent nonsynonymous substitutions in the e...
Autores principales: | Muraski, Marc J., Nilsson, Emil M., Fritz, Melissa J., Richardson, Anthony R., Alexander, Rebecca W., Cooper, Vaughn S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128029/ https://www.ncbi.nlm.nih.gov/pubmed/36853041 http://dx.doi.org/10.1128/mbio.00287-23 |
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