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Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi

Outer surface protein C (OspC) plays a pivotal role in mediating tick-to-host transmission and infectivity of the Lyme disease spirochete, Borreliella burgdorferi. OspC is a helical-rich homodimer that interacts with tick salivary proteins, as well as components of the mammalian immune system. Sever...

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Detalles Bibliográficos
Autores principales: Rudolph, Michael J., Davis, Simon A., Haque, H. M. Emranul, Weis, David D., Vance, David J., Piazza, Carol Lyn, Ejemel, Monir, Cavacini, Lisa, Wang, Yang, Mbow, M. Lamine, Gilmore, Robert D., Mantis, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128040/
https://www.ncbi.nlm.nih.gov/pubmed/36976016
http://dx.doi.org/10.1128/mbio.02981-22