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Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi
Outer surface protein C (OspC) plays a pivotal role in mediating tick-to-host transmission and infectivity of the Lyme disease spirochete, Borreliella burgdorferi. OspC is a helical-rich homodimer that interacts with tick salivary proteins, as well as components of the mammalian immune system. Sever...
Autores principales: | Rudolph, Michael J., Davis, Simon A., Haque, H. M. Emranul, Weis, David D., Vance, David J., Piazza, Carol Lyn, Ejemel, Monir, Cavacini, Lisa, Wang, Yang, Mbow, M. Lamine, Gilmore, Robert D., Mantis, Nicholas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128040/ https://www.ncbi.nlm.nih.gov/pubmed/36976016 http://dx.doi.org/10.1128/mbio.02981-22 |
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