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Adjunctive Integrated Stress Response Inhibition Accelerates Tuberculosis Clearance in Mice

Despite numerous advances in tuberculosis (TB) drug development, long treatment durations have led to the emergence of multidrug resistance, which poses a major hurdle to global TB control. Shortening treatment time therefore remains a top priority. Host-directed therapies that promote bacterial cle...

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Detalles Bibliográficos
Autores principales: Krug, Stefanie, Prasad, Pankaj, Xiao, Shiqi, Lun, Shichun, Ruiz-Bedoya, Camilo A., Klunk, Mariah, Ordonez, Alvaro A., Jain, Sanjay K., Srikrishna, Geetha, Kramnik, Igor, Bishai, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128048/
https://www.ncbi.nlm.nih.gov/pubmed/36853048
http://dx.doi.org/10.1128/mbio.03496-22