Exaptation of Inactivated Host Enzymes for Structural Roles in Orthopoxviruses and Novel Folds of Virus Proteins Revealed by Protein Structure Modeling

Viruses with large, double-stranded DNA genomes captured the majority of their genes from their hosts at different stages of evolution. The origins of many virus genes are readily detected through significant sequence similarity with cellular homologs. In particular, this is the case for virus enzym...

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Detalles Bibliográficos
Autores principales: Mutz, Pascal, Resch, Wolfgang, Faure, Guilhem, Senkevich, Tatiana G., Koonin, Eugene V., Moss, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128050/
https://www.ncbi.nlm.nih.gov/pubmed/37017580
http://dx.doi.org/10.1128/mbio.00408-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128050/
https://www.ncbi.nlm.nih.gov/pubmed/37017580
http://dx.doi.org/10.1128/mbio.00408-23

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