CRISPR Screens Identify Toxoplasma Genes That Determine Parasite Fitness in Interferon Gamma-Stimulated Human Cells

Toxoplasma virulence depends on its ability to evade or survive the toxoplasmacidal mechanisms induced by interferon gamma (IFNγ). While many Toxoplasma genes involved in the evasion of the murine IFNγ response have been identified, genes required to survive the human IFNγ response are largely unkno...

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Detalles Bibliográficos
Autores principales: Krishnamurthy, Shruthi, Maru, Parag, Wang, Yifan, Bitew, Mebratu A., Mukhopadhyay, Debanjan, Yamaryo-Botté, Yoshiki, Paredes-Santos, Tatiana C., Sangaré, Lamba O., Swale, Christopher, Botté, Cyrille Y., Saeij, Jeroen P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128063/
https://www.ncbi.nlm.nih.gov/pubmed/36916910
http://dx.doi.org/10.1128/mbio.00060-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128063/
https://www.ncbi.nlm.nih.gov/pubmed/36916910
http://dx.doi.org/10.1128/mbio.00060-23

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