Mutations in rpoB That Confer Rifampicin Resistance Can Alter Levels of Peptidoglycan Precursors and Affect β-Lactam Susceptibility

Bacteria can adapt to stressful conditions through mutations affecting the RNA polymerase core subunits that lead to beneficial changes in transcription. In response to selection with rifampicin (RIF), mutations arise in the RIF resistance-determining region (RRDR) of rpoB that reduce antibiotic bin...

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Detalles Bibliográficos
Autores principales: Patel, Yesha, Soni, Vijay, Rhee, Kyu Y., Helmann, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128067/
https://www.ncbi.nlm.nih.gov/pubmed/36779708
http://dx.doi.org/10.1128/mbio.03168-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128067/
https://www.ncbi.nlm.nih.gov/pubmed/36779708
http://dx.doi.org/10.1128/mbio.03168-22

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