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A Fijivirus Major Viroplasm Protein Shows RNA-Stimulated ATPase Activity by Adopting Pentameric and Hexameric Assemblies of Dimers

Fijiviruses replicate and package their genomes within viroplasms in a process involving RNA-RNA and RNA-protein interactions. Here, we demonstrate that the 24 C-terminal residues (C-arm) of the P9-1 major viroplasm protein of the mal de Río Cuarto virus (MRCV) are required for its multimerization a...

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Detalles Bibliográficos
Autores principales: Llauger, Gabriela, Melero, Roberto, Monti, Demián, Sycz, Gabriela, Huck-Iriart, Cristián, Cerutti, María L., Klinke, Sebastián, Mikkelsen, Evelyn, Tijman, Ariel, Arranz, Rocío, Alfonso, Victoria, Arellano, Sofía M., Goldbaum, Fernando A., Sterckx, Yann G. J., Carazo, José-María, Kaufman, Sergio B., Dans, Pablo D., del Vas, Mariana, Otero, Lisandro H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128069/
https://www.ncbi.nlm.nih.gov/pubmed/36786587
http://dx.doi.org/10.1128/mbio.00023-23