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Virtual Screening and Biological Evaluation of Novel Low Molecular Weight Protein Tyrosine Phosphatase Inhibitor for the Treatment of Insulin Resistance

PURPOSE: Protein tyrosine phosphatases (PTPs) play an essential way in diseases including cancer, obesity, diabetes and autoimmune disorders. As a member of PTPs, low molecular weight PTP (LMPTP) has been a well-recognized anti-insulin resistance target in obesity. However, the number of reported LM...

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Detalles Bibliográficos
Autores principales: Feng, Bo, Dong, Xu, Liu, Zhen, Zhang, Jie, Liu, Hongyu, Xu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128076/
https://www.ncbi.nlm.nih.gov/pubmed/37113468
http://dx.doi.org/10.2147/DDDT.S406956