Nrf2(−/−) regulated lung DNA demethylation and CYP2E1 DNA methylation under PM(2.5) exposure

Cytochrome P450 (CYP450) can mediate fine particulate matter (PM(2.5)) exposure leading to lung injury. Nuclear factor E2-related factor 2 (Nrf2) can regulate CYP450 expression; however, the mechanism by which Nrf2(−/−) (KO) regulates CYP450 expression via methylation of its promoter after PM(2.5) e...

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Detalles Bibliográficos
Autores principales: Wu, Mengjie, Jiang, Menghui, Ding, Hao, Tang, Siying, Li, Daochuan, Pi, Jingbo, Zhang, Rong, Chen, Wen, Chen, Rui, Zheng, Yuxin, Piao, Jinmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128193/
https://www.ncbi.nlm.nih.gov/pubmed/37113990
http://dx.doi.org/10.3389/fgene.2023.1144903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128193/
https://www.ncbi.nlm.nih.gov/pubmed/37113990
http://dx.doi.org/10.3389/fgene.2023.1144903

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