Discovery of the first-in-class potent and isoform-selective human carbonic anhydrase III inhibitors

Considering the unrecognised physio-pathological role of human carbonic anhydrase III (hCA III), a structure-based drug design was set up to identify the first-in-class potent and selective inhibitors of this neglected isoform. hCA III targeting was planned considering a unique feature of its active...

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Detalles Bibliográficos
Autores principales: Giovannuzzi, Simone, Bonardi, Alessandro, Gratteri, Paola, Nocentini, Alessio, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128460/
https://www.ncbi.nlm.nih.gov/pubmed/37092262
http://dx.doi.org/10.1080/14756366.2023.2202360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128460/
https://www.ncbi.nlm.nih.gov/pubmed/37092262
http://dx.doi.org/10.1080/14756366.2023.2202360

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