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Sanguinarine inhibits melanoma invasion and migration by targeting the FAK/PI3K/AKT/mTOR signalling pathway

CONTEXT: Sanguinarine (SAG) is the most abundant constituent of Macleaya cordata (Willd.) R. Br. (Popaceae). SAG has shown antimammary and colorectal metastatic effects in mice in vivo, suggesting its potential for cancer chemotherapy. OBJECTIVE: To determine the antimetastatic effect and underlying...

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Detalles Bibliográficos
Autores principales: Qi, Xiaoyi, Chen, Yonglan, Liu, Sha, Liu, Li, Yu, Zehui, Yin, Ling, Fu, Lu, Deng, Mingming, Liang, Sicheng, Lü, Muhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128503/
https://www.ncbi.nlm.nih.gov/pubmed/37092313
http://dx.doi.org/10.1080/13880209.2023.2200787