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High concordance rate of capillary electrophoresis workflow for microsatellite instability analysis and mismatch repair (MMR) immunostaining in colorectal carcinoma

Microsatellite instability (MSI) is the primary predictive biomarker for therapeutic efficacies of cancer immunotherapies. Establishment of the MSI detection methods with high sensitivity and accessibility is important. Because MSI is mainly caused by defects in DNA mismatch repair (MMR), immunohist...

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Detalles Bibliográficos
Autores principales: Huang, Wenya, Ho, Chung-Liang, Lee, Chung-Ta, Chen, Wan-Li, Yang, Shu-Ching, Chow, Nan-Haw, Chen, Yi-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10128978/
https://www.ncbi.nlm.nih.gov/pubmed/37098015
http://dx.doi.org/10.1371/journal.pone.0284227