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Neurochemical Profile of BRAF(V600E)/Akt(T308D/S473D) Mouse Gangliogliomas Reveals Impaired GABAergic System Inhibition

Gangliogliomas (GGs), composed of dysmorphic neurons and neoplastic astroglia, represent the most frequent tumor entity associated with chronic recurrent epileptic seizures. So far, a systematic analysis of potential differences in neurochemical profiles of dysmorphic tumoral neurons as well as neur...

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Detalles Bibliográficos
Autores principales: Kyriazi, Maria, Müller, Philipp, Pitsch, Julika, van Loo, Karen M.J., Quatraccioni, Anne, Opitz, Thoralf, Schoch, Susanne, Becker, Albert J., Cases-Cunillera, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129025/
https://www.ncbi.nlm.nih.gov/pubmed/36538906
http://dx.doi.org/10.1159/000528587