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Activation and Speciation Mechanisms in Class A GPCRs

Accurate development of allosteric modulators of GPCRs require a thorough assessment of their sequence, structure, and dynamics, toward gaining insights into their mechanisms of actions shared by family members, as well as dynamic features that distinguish subfamilies. Building on recent progress in...

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Detalles Bibliográficos
Autores principales: Wingert, Bentley, Doruker, Pemra, Bahar, Ivet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129049/
https://www.ncbi.nlm.nih.gov/pubmed/35728652
http://dx.doi.org/10.1016/j.jmb.2022.167690