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Depicting pseudotime-lagged causality across single-cell trajectories for accurate gene-regulatory inference

Identifying the causal interactions in gene-regulatory networks requires an accurate understanding of the time-lagged relationships between transcription factors and their target genes. Here we describe DELAY (short for Depicting Lagged Causality), a convolutional neural network for the inference of...

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Detalles Bibliográficos
Autores principales: Reagor, Caleb C, Velez-Angel, Nicolas, Hudspeth, A J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129065/
https://www.ncbi.nlm.nih.gov/pubmed/37113980
http://dx.doi.org/10.1093/pnasnexus/pgad113