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Honokiol attenuates mitochondrial fission and cell apoptosis by activating Sirt3 in intracerebral hemorrhage

BACKGROUND: Sirtuin-3 (Sirt3) has been documented to protect against mitochondrial dysfunction and apoptosis. Honokiol (HKL) is a Sirt3 pharmacological activator with reported neuroprotective effects in multiple neurological disorders. The present study aimed to explore the neuroprotective effects o...

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Detalles Bibliográficos
Autores principales: Zheng, Xuecheng, Gao, Junling, Zhao, Manman, Han, Lingling, Zhang, Dexin, Wang, Kaijie, Cui, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129194/
https://www.ncbi.nlm.nih.gov/pubmed/36805606
http://dx.doi.org/10.1097/CM9.0000000000002178