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Svep1 is a binding ligand of Tie1 and affects specific aspects of facial lymphatic development in a Vegfc-independent manner

Multiple factors are required to form functional lymphatic vessels. Here, we uncover an essential role for the secreted protein Svep1 and the transmembrane receptor Tie1 during the development of subpopulations of the zebrafish facial lymphatic network. This specific aspect of the facial network for...

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Detalles Bibliográficos
Autores principales: Hußmann, Melina, Schulte, Dörte, Weischer, Sarah, Carlantoni, Claudia, Nakajima, Hiroyuki, Mochizuki, Naoki, Stainier, Didier YR, Zobel, Thomas, Koch, Manuel, Schulte-Merker, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129328/
https://www.ncbi.nlm.nih.gov/pubmed/37097004
http://dx.doi.org/10.7554/eLife.82969